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Clinical trials for Left Anterior Descending Coronary Artery

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    Clinical Trials Information System (CTIS).


    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    19 result(s) found for: Left Anterior Descending Coronary Artery. Displaying page 1 of 1.
    EudraCT Number: 2007-003492-39 Sponsor Protocol Number: BR1-125 Start Date*: 2008-04-29
    Sponsor Name:Bracco Imaging S.p.A.
    Full Title: A phase III study to compare SonoVue® enhanced myocardial echocardiography (MCE) to single photon emission computerized tomography (ECG-GATED SPECT), at rest and at peak of low-dose Dipyridamole s...
    Medical condition: Suspected coronary artery disease (CAD) indicated for stress ECG-gated SPECT and coronary angiography to clarify whether they have a clinical significant coronary stenosis (=70%).
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011085 Ischaemic coronary artery disorders HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Completed) BE (Completed) NL (Completed) GB (Completed) IT (Completed) ES (Completed) GR (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2008-004881-16 Sponsor Protocol Number: P05633 Start Date*: 2009-06-10
    Sponsor Name:Schering-Plough Research Institute, a Division of Schering Corporation
    Full Title: The Effect of Acadesine on Clinically Significant Adverse Cardiovascular and Cerebrovascular Events in High-Risk Subjects Undergoing Coronary Artery Bypass Graft (CABG) Surgery Using Cardiopulmonar...
    Medical condition: Coronary artery disease
    Disease: Version SOC Term Classification Code Term Level
    9.1 10011078 Coronary artery disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Prematurely Ended) ES (Prematurely Ended) DE (Completed) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-002293-54 Sponsor Protocol Number: Apex01version6 Start Date*: 2007-11-29
    Sponsor Name:University of Dundee
    Full Title: The APEX Trial: Effects of Allopurinol on Coronary and Peripheral Endothelial Function in Patients with Cardiac Syndrome X
    Medical condition: Patients with cardiac syndrome X (typical anginal-like chest pain and normal coronary arteriograms)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2015-003260-37 Sponsor Protocol Number: 1060 Start Date*: 2015-10-22
    Sponsor Name:Liverpool Heart and Chest Hospital
    Full Title: Can Ivabradine attenuate post-revascularisation microcirculatory dysfunction in flow limiting coronary artery disease?
    Medical condition: Coronary Artery Disease/Angina
    Disease: Version SOC Term Classification Code Term Level
    18.1 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    18.1 10007541 - Cardiac disorders 10011073 Coronary artery atheroma LLT
    18.1 10007541 - Cardiac disorders 10002372 Angina LLT
    18.1 10007541 - Cardiac disorders 10003600 Atheroma coronary artery LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2010-020497-41 Sponsor Protocol Number: ANG.AMI-IC001 Start Date*: 2013-02-13
    Sponsor Name:Mesoblast, Inc.
    Full Title: A prospective, double blind, randomized, placebo-controlled clinical trial of intracoronary infusion of immunoselected, bone marrow-derived Stro3 mesenchymal precursor cells (MPC) in the treatment ...
    Medical condition: ST-elevation myocardial infarction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10064345 ST segment elevation myocardial infarction LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BE (Ongoing) NL (Completed) DK (Completed) SE (Completed) CZ (Completed) AT (Prematurely Ended) PL (Completed) IT (Prematurely Ended) ES (Completed) PT (Ongoing)
    Trial results: View results
    EudraCT Number: 2007-002617-39 Sponsor Protocol Number: Fondazione Mediolanum 001/2007 Start Date*: 2008-01-23
    Sponsor Name:Fondazione Mediolanum Onlus
    Full Title: INtegrilin plus STenting to Avoid Myocardial Necrosis Trial
    Medical condition: Patients with diffuse CAD undergoing percutaneous treatment on a native coronary vessel with planned implantation of two DES in overlapping with a total stent length 33 mm for diffuse coronary dis...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10051592 Acute coronary syndrome LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2019-004433-17 Sponsor Protocol Number: 124210 Start Date*: 2020-02-18
    Sponsor Name:MRC CTU at UCL
    Full Title: Multi-centre, randomised, open-label, blinded endpoint assessed, trial of corticosteroids plus intravenous immunoglobulin (IVIG) and aspirin, versus IVIG and aspirin for prevention of coronary arte...
    Medical condition: Kawasaki Disease
    Disease: Version SOC Term Classification Code Term Level
    20.0 10047065 - Vascular disorders 10023320 Kawasaki's disease PT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) BE (Ongoing) EE (Ongoing) SE (Ongoing) FI (Ongoing) ES (Ongoing) DE (Ongoing) NL (Ongoing) IT (Ongoing) AT (Ongoing) CZ (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-002226-79 Sponsor Protocol Number: AUGEAS Start Date*: Information not available in EudraCT
    Sponsor Name:Region Skåne
    Full Title: A 30-day, randomized, evalUator-blind, controlled, multi-centre, parallel Group, phase III study to evaluate the Effect of a Low Maintenance Dose TicAgrelor Regimen versus Standard Dose Clopidogrel...
    Medical condition: Coronary Artery Disease (CAD)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10011078 Coronary artery disease PT
    20.0 10007541 - Cardiac disorders 10072685 Microvascular coronary artery disease PT
    21.1 10027433 - Metabolism and nutrition disorders 10067585 Type 2 diabetes mellitus PT
    21.1 10042613 - Surgical and medical procedures 10065608 Percutaneous coronary intervention PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-002563-10 Sponsor Protocol Number: BAY86-4875/15961 Start Date*: 2013-06-06
    Sponsor Name:Bayer HealthCare AG
    Full Title: Multicenter open-label study to evaluate efficacy of gadobutrol-enhanced cardiac magnetic resonance imaging (CMRI) for detection of significant coronary artery disease (CAD) in subjects with known ...
    Medical condition: Subjects with known or suspected Coronary Artery Disease (CAD)
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed) GB (Completed) FR (Completed)
    Trial results: View results
    EudraCT Number: 2007-004620-20 Sponsor Protocol Number: P3 Start Date*: 2008-05-21
    Sponsor Name:department of Pharmacology-Toxicology RUNMC
    Full Title: Persantin Preceding PCI
    Medical condition: myocardial damage due to PCI
    Disease: Version SOC Term Classification Code Term Level
    9.1 10065554 Myocardial infarction prophylaxis LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2010-024616-33 Sponsor Protocol Number: TRO40303CLEQ1491-1 Start Date*: 2011-08-04
    Sponsor Name:TROPHOS SA
    Full Title: Phase II, multicenter, randomized, double-blind, placebo controlled study to assess safety and efficacy of TRO40303 for reduction of reperfusion injury in patients undergoing Percutaneous Coronary ...
    Medical condition: Treatment for cardiac reperfusion injury in patients undergoing PCI( Percutaneous coronary intervention) to treat an AMI (Acute Myocardial Infarction) and to assess safety as well as the ability of...
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000930 Acute myocardial infarction, unspecified site, initial episode of care LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed) SE (Completed)
    Trial results: (No results available)
    EudraCT Number: 2010-022725-16 Sponsor Protocol Number: RE-0240/2010/EN Start Date*: 2012-03-30
    Sponsor Name:FRANCISCO JOSE MORALES PONCE
    Full Title: INTRACORONARY ADMINISTRATION OF TENECTEPLASE VERSUS ABCIXIMAB AS ADJUNCTIVE TREATMENT DURING PRIMARY ANGIOPLASTY IN ACUTE MYOCARDIAL INFARCTION OF ANTERIOR LOCATION
    Medical condition: ACUTE MYOCARDIAL INFARCTION
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10000894 Acute myocardial infarction, of anterolateral wall, initial episode of care LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2018-003676-12 Sponsor Protocol Number: ATH3G10-006 Start Date*: 2018-12-17
    Sponsor Name:Athera Biotechnologies AB
    Full Title: A phase IIa, placebo-controlled, double blind, randomised multicentre pilot study to investigate the efficacy, safety and tolerability of the monoclonal antibody ATH3G10 in patients with ST-elevati...
    Medical condition: Treatment of ST-elevated myocardial infarction (STEMI) after percutaneous intervention (PCI)
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    20.0 10007541 - Cardiac disorders 10064346 STEMI LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Completed) DK (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2009-013425-42 Sponsor Protocol Number: 901 Start Date*: 2009-08-14
    Sponsor Name:Atrium Medical Corporation [...]
    1. Atrium Medical Corporation
    2. Cardiovascular Research Foundation
    Full Title: A 2x2 Factorial, Randomized, Multicenter, Single-Blind Evaluation of Intracoronary Abciximab Infusion and Aspiration Thrombectomy in Patients Undergoing Percutaneous Coronary Intervention for Anter...
    Medical condition: The study population will consist of up to 452 male and female subjects with anterior STEMI and occluded proximal or mid LAD with TIMI 0/1 flow with indication for primary PCI.
    Disease: Version SOC Term Classification Code Term Level
    9.1 10000891 Acute myocardial infarction LLT
    9.1 10000904 Acute myocardial infarction, of other anterior wall LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) DE (Completed) AT (Completed) GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2004-005252-14 Sponsor Protocol Number: KAI-9803-001 Start Date*: 2005-04-21
    Sponsor Name:KAI Pharmaceuticals Incorporated
    Full Title: Direct Inhibition of δ Protein Kinase C Enzyme to Limit Total Infarct Size in Acute Myocardial Infarction (DELTA MI): Intracoronary KAI-9803 for Injection as an Adjunct to Primary Percutaneous Coro...
    Medical condition: Acute myocardial infarction with ST elevation
    Disease: Version SOC Term Classification Code Term Level
    7.1 10000891 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: AT (Completed) CZ (Completed) DE (Completed)
    Trial results: View results
    EudraCT Number: 2015-002322-40 Sponsor Protocol Number: 20140254 Start Date*: 2016-01-13
    Sponsor Name:Amgen Inc
    Full Title: A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Effect of AMG 334 on Exercise Time During a Treadmill Test in Subjects With Stable Angina
    Medical condition: Migraine Prevention
    Disease: Version SOC Term Classification Code Term Level
    19.1 10029205 - Nervous system disorders 10027599 Migraine PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SK (Completed) BG (Completed) DE (Prematurely Ended) LV (Completed) CZ (Completed) PL (Completed)
    Trial results: View results
    EudraCT Number: 2008-000561-28 Sponsor Protocol Number: SOSP- CLOP Start Date*: 2008-05-08
    Sponsor Name:AZIENDA OSPEDALIERA OSPEDALE NIGUARDA CA` GRANDA (A.O. DI RILIEVO NAZIONALE)
    Full Title: Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of bridging antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel.
    Medical condition: prevention of cardiac ischemic events in patients undergoing major or ocular surgery
    Disease: Version SOC Term Classification Code Term Level
    9.1 10007541 SOC
    9.1 10007541 SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2018-002895-42 Sponsor Protocol Number: D6580C00003 Start Date*: 2018-11-22
    Sponsor Name:AstraZeneca AB
    Full Title: A randomized, double blind, placebo-controlled, parallel group, multicentre, phase 2a study to assess target engagement, safety and tolerability of AZD4831 in patients with Heart Failure with prese...
    Medical condition: Heart failure with preserved Ejection Fraction (HFpEF) and heart failure with mid-range Ejection Fraction (HFmrEF)
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Prematurely Ended) DK (Prematurely Ended) FI (Completed) NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2009-017242-30 Sponsor Protocol Number: D5132C00001 Start Date*: 2010-12-06
    Sponsor Name:AstraZeneca AB
    Full Title: A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multinational Trial, to Assess the Prevention of Thrombotic Events with Ticagrelor Compared to Placebo on a Background of Acetyl Sali...
    Medical condition: Myocardial Infarction, Cardiovascular Death, Atherothombosis, Stroke
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004849 10007648 Cardiovascular disease, unspecified LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed) GB (Completed) DE (Completed) HU (Completed) RO (Completed) CZ (Completed) SK (Completed) PL (Completed) BE (Completed) ES (Completed) SE (Completed) IT (Completed) NO (Completed) BG (Completed)
    Trial results: View results
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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